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Psychobiology of Co-Occurring Disorders

Neurobiology of Addiction
Dr. Dawn-Elise Snipes
Objectives
- Review how tolerance develops
- Discuss the impact of addictive substances and behaviors on the brain and body
Tolerance (Addiction or Physiological or Physical Stress)
- The brain tries to maintain homeostasis in the body (warm bath)
- When you take drugs or experience stress it increases the levels of certain neurotransmitters (stimulants = hot water; depressants=cold water)
- To normalize the chemical levels the brain for survival, the brain “balances the temperature”
- Increases the secretion or receptor activation of the opposite neurotransmitters
- Reduces activation of targeted receptors (cortisol, glutamate etc.)
- To get the same high, more or different triggers are needed
- Withdrawal triggers opposing physiological and psychological symptoms
$18.00 for 90 days

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